TY - GEN AU - Povedano, Eloy AU - Vargas, Eva AU - Ruiz-Valdepeñas Montiel, Víctor AU - Torrente-Rodríguez, Rebeca M AU - Pedrero, María AU - Barderas Manchado, Rodrigo AU - Segundo-Acosta, Pablo San AU - Peláez-García, Alberto AU - Mendiola, Marta AU - Hardisson, David AU - Campuzano, Susana AU - Pingarrón, José M PY - 2018 DO - 10.1038/s41598-018-24902-1 SN - 2045-2322 UR - http://hdl.handle.net/20.500.12105/9149 AB - This paper describes two different electrochemical affinity biosensing approaches for the simple, fast and bisulfite and PCR-free quantification of 5-methylated cytosines (5-mC) in DNA using the anti-5-mC antibody as biorecognition element. One of the... LA - eng PB - Nature Publishing Group KW - Body Fluids KW - Brain Neoplasms KW - DNA Modification Methylases KW - DNA Repair Enzymes KW - Electrochemical Techniques KW - Electrodes KW - Glioblastoma KW - Humans KW - Limit of Detection KW - Sulfates KW - Tumor Suppressor Proteins KW - Biosensing Techniques KW - DNA Methylation TI - Electrochemical affinity biosensors for fast detection of gene-specific methylations with no need for bisulfite and amplification treatments TY - research article ER -