TY  - GEN
AU  - Barbas, Ana
AU  - Matos, Rute G
AU  - Amblar, Monica
AU  - López-Viñas, Eduardo
AU  - Gomez-Puertas, Paulino
AU  - Arraiano, Cecília Maria
PY  - 2009
DO  - 10.1074/jbc.M109.020693
UR  - http://hdl.handle.net/20.500.12105/16652
AB  - RNase II is the prototype of a ubiquitous family of enzymes that are crucial for RNA metabolism. In Escherichia coli this protein is a single-stranded-specific 3'-exoribonuclease with a modular organization of four functional domains. In eukaryotes,...
LA  - eng
PB  - American Society for Biochemistry and Molecular Biology (ASBMB)
KW  - Biocatalysis
KW  - Amino Acid Substitution
KW  - Amino Acids
KW  - Conserved Sequence
KW  - DNA
KW  - Escherichia coli
KW  - Exoribonucleases
KW  - Kinetics
KW  - Models, Molecular
KW  - Mutant Proteins
KW  - Mutation
KW  - Protein Binding
KW  - Protein Conformation
KW  - RNA
KW  - Substrate Specificity
KW  - Surface Plasmon Resonance
TI  - Determination of key residues for catalysis and RNA cleavage specificity: one mutation turns RNase II into a "SUPER-ENZYME"
TY  - research article
ER  -