TY  - JOUR
AU  - Chattopadhyay, Mrittika
AU  - Jenkins, Edmund Charles
AU  - Lechuga-Vieco, Ana Victoria
AU  - Nie, Kai
AU  - Fiel, Maria Isabel
AU  - Rialdi, Alexander
AU  - Guccione, Ernesto
AU  - Enriquez, Jose Antonio
AU  - Sia, Daniela
AU  - Lujambio, Amaia
AU  - Germain, Doris
PY  - 2022
DO  - 10.1016/j.celrep.2021.110254
UR  - http://hdl.handle.net/20.500.12105/15666
AB  - Cancer heterogeneity and evolution are not fully understood. Here, we show that mitochondrial DNA of the normal liver shapes tumor progression, histology, and immune environment prior to the acquisition of oncogenic mutation. Using conplastic mice, we...
LA  - eng
PB  - Cell Press
KW  - Animals
KW  - Carcinoma, Hepatocellular
KW  - DNA, Mitochondrial
KW  - Female
KW  - Humans
KW  - Liver Neoplasms
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Pregnancy-Associated Plasma Protein-A
KW  - Transcriptome
KW  - Unfolded Protein Response
TI  - The portrait of liver cancer is shaped by mitochondrial genetics.
TY  - journal article
ER  -