TY - JOUR AU - Triana-Martínez, Francisco AU - Picallos-Rabina, Pilar AU - Da Silva-Álvarez, Sabela AU - Pietrocola, Federico AU - LLanos, Susana AU - Rodilla, Verónica AU - Soprano, Enrica AU - Pedrosa, Pablo AU - Ferreirós, Alba AU - Barradas, Marta AU - Hernández-González, Fernanda AU - Lalinde, Marta AU - Prats, Neus AU - Bernadó, Cristina AU - Gonzalez, Patricia AU - Gómez, María AU - Ikonomopoulou, Maria P AU - Fernández-Marcos, Pablo J AU - García-Caballero, Tomás AU - Del Pino, Pablo AU - Arribas, Joaquín AU - Vidal, Anxo AU - González-Barcia, Miguel AU - Serrano Marugan, Manuel AU - Loza, María I AU - Domínguez, Eduardo AU - Collado, Manuel PY - 2019 DO - 10.1038/s41467-019-12888-x SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/9318 AB - Compounds with specific cytotoxic activity in senescent cells, or senolytics, support the causal involvement of senescence in aging and offer therapeutic interventions. Here we report the identification of Cardiac Glycosides (CGs) as a family of... LA - eng PB - Nature Publishing Group KW - A549 Cells KW - Animals KW - Antibiotics, Antineoplastic KW - Apoptosis KW - Bleomycin KW - Breast Neoplasms KW - Cardiac Glycosides KW - Cell Line, Tumor KW - Cell Membrane KW - Cellular Senescence KW - Chondrocytes KW - Digoxin KW - Female KW - Fibroblasts KW - Humans KW - Hydrogen-Ion Concentration KW - Mice KW - Osteoarthritis KW - Ouabain KW - Proscillaridin KW - Pulmonary Fibrosis KW - Xenograft Model Antitumor Assays TI - Identification and characterization of Cardiac Glycosides as senolytic compounds TY - journal article ER -