TY - JOUR AU - Lopez-Huertas, Maria Rosa AU - Jiménez-Tormo, Laura AU - Madrid-Elena, Nadia AU - Gutiérrez, Carolina AU - Rodríguez-Mora, Sara AU - Coiras, Mayte AU - Alcamí, José AU - Moreno, Santiago PY - 2017 DO - 10.1038/s41598-017-02634-y SN - 2045-2322 UR - http://hdl.handle.net/20.500.12105/7333 AB - A potential strategy to cure HIV-1 infection is to use latency reversing agents (LRAs) to eliminate latent reservoirs established in resting CD4+ T (rCD4+) cells. As no drug has been shown to be completely effective, finding new drugs and combinations... LA - eng PB - Nature Publishing Group KW - Maraviroc KW - Bryostatin KW - HIV latency KW - HIV cure KW - LRA KW - Bryostatins KW - CCR5 Receptor Antagonists KW - CD4-Positive T-Lymphocytes KW - Cell Proliferation KW - Chemokine CCL19 KW - Gene Expression Regulation KW - HIV-1 KW - Humans KW - Interleukin-7 KW - Maraviroc KW - NF-kappa B KW - Primary Cell Culture KW - Protein Kinase C KW - Receptors, CCR5 KW - Signal Transduction KW - Virus Latency KW - Virus Replication KW - Host-Pathogen Interactions TI - The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1 TY - journal article ER -