TY - GEN AU - Abarrategi, Ander AU - Gambera, Stefano AU - Alfranca, Arantzazu AU - Rodriguez-Milla, Miguel A AU - Perez-Tavarez, Raquel AU - Rouault-Pierre, Kevin AU - Waclawiczek, Alexander AU - Chakravarty, Probir AU - Mulero, Francisca AU - Trigueros, César AU - Navarro, Samuel AU - Bonnet, Dominique AU - Garcia-Castro, Javier PY - 2018 DO - 10.1038/s41598-018-33689-0 SN - 2045-2322 UR - http://hdl.handle.net/20.500.12105/9136 AB - Mesenchymal progenitor cells (MPCs) have been hypothesized as cells of origin for sarcomas, and c-Fos transcription factor has been showed to act as an oncogene in bone tumors. In this study, we show c-Fos is present in most sarcomas with chondral... LA - eng PB - Nature Publishing Group KW - Animals KW - Carcinogenesis KW - Cell Line KW - Cell Transformation, Neoplastic KW - Gene Expression Regulation, Neoplastic KW - Genes, fos KW - Humans KW - Mesenchymal Stem Cells KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - Proto-Oncogene Proteins c-fos KW - Sarcoma TI - c-Fos induces chondrogenic tumor formation in immortalized human mesenchymal progenitor cells TY - research article ER -