TY - GEN AU - Gomez, Sara AU - Querol-Garcia, Javier AU - Sanchez-Barron, Gara AU - Subias, Marta AU - Gonzalez-Alsina, Alex AU - Franco-Hidalgo, Virginia AU - Alberti, Sebastian AU - Rodriguez de Cordoba, Santiago AU - Fernandez, Francisco J AU - Cristina Vega, M PY - 2019 DO - 10.3389/fmicb.2019.00326 SN - 1664-302X UR - https://hdl.handle.net/20.500.12105/22707 AB - The ubiquitous and highly abundant glycolytic enzyme D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pivotal for the energy and carbon metabolism of most organisms, including human pathogenic bacteria. For bacteria that depend mostly on... LA - eng PB - Frontiers Media KW - GAPDH - glyceraldehyde-3-phosphate dehydrogenase KW - Streptococcus pyogenes KW - Clostridium perfringens KW - Anacardic acid KW - Curcumin KW - Complement - immunological term KW - Enzyme inhibition KW - X-ray crystallography TI - The Antimicrobials Anacardic Acid and Curcumin Are Not-Competitive Inhibitors of Gram-Positive Bacteria Pathogenic Glyceraldehyde-3-Phosphate Dehydrogenase by a Mechanism Unrelated to Human C5a Anaphylatoxin Binding TY - research article ER -