TY  - JOUR
AU  - Santos, María
AU  - Niemi, Mikko
AU  - Hiratsuka, Masahiro
AU  - Kumondai, Masaki
AU  - Ingelman-Sundberg, Magnus
AU  - Lauschke, Volker M
AU  - Rodriguez Antona, Cristina
PY  - 2018
DO  - 10.1038/gim.2017.156
UR  - http://hdl.handle.net/20.500.12105/17509
AB  - PurposeVariability in pharmacokinetics and drug response is shaped by single-nucleotide variants (SNVs) as well as copy-number variants (CNVs) in genes with importance for drug absorption, distribution, metabolism, and excretion (ADME). While SNVs...
LA  - eng
PB  - Elsevier
KW  - Alleles
KW  - Biomarkers, Pharmacological
KW  - Cytochrome P-450 CYP2C19
KW  - Cytochrome P450 Family 4
KW  - DNA Copy Number Variations
KW  - Databases, Genetic
KW  - Exome
KW  - Gene Frequency
KW  - Genotype
KW  - High-Throughput Nucleotide Sequencing
KW  - Humans
KW  - Oligonucleotide Array Sequence Analysis
KW  - Pharmacogenetics
KW  - Pharmacogenomic Variants
KW  - Pharmacokinetics
KW  - Polymorphism, Single Nucleotide
KW  - Sequence Analysis, DNA
KW  - Solute Carrier Organic Anion Transporter Family Member 1B3
TI  - Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics.
TY  - journal article
ER  -