TY  - GEN
AU  - Rodriguez-Cortez, Virginia C
AU  - del Pino-Molina, Lucia
AU  - Rodriguez-Ubreva, Javier
AU  - Ciudad, Laura
AU  - Gomez-Cabrero, David
AU  - Company, Carlos
AU  - Urquiza, Jose M
AU  - Tegner, Jesper
AU  - Rodriguez-Gallego, Carlos
AU  - Lopez-Granados, Eduardo
AU  - Ballestar, Esteban
PY  - 2015
DO  - 10.1038/ncomms8335
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/20121
AB  - Common variable immunodeficiency (CVID), the most frequent primary immunodeficiency characterized by loss of B-cell function, depends partly on genetic defects, and epigenetic changes are thought to contribute to its aetiology. Here we perform a...
LA  - eng
PB  - Nature Publishing Group
KW  - Immunologic Memory
KW  - B-Lymphocytes
KW  - Case-Control Studies
KW  - DNA Methylation
KW  - Common Variable Immunodeficiency
KW  - Gene Expression Regulation
KW  - Humans
KW  - Twins, Monozygotic
TI  - Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naive-to-memory B-cell transition
TY  - research article
ER  -