TY  - GEN
AU  - Lozano, Rebeca
AU  - Castro, Elena
AU  - Aragón, Isabel M
AU  - Cendón, Ylenia
AU  - Cattrini, Carlo
AU  - López-Casas, Pedro P
AU  - Olmos, David
PY  - 2020
DO  - 10.1038/s41416-020-01114-x
UR  - http://hdl.handle.net/20.500.12105/18138
AB  - Over the past years, several studies have demonstrated that defects in DNA damage response and repair (DDR) genes are present in a significant proportion of patients with prostate cancer. These alterations, particularly mutations in BRCA2, are known...
LA  - eng
KW  - Antineoplastic Agents
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Clinical Trials as Topic
KW  - DNA Damage
KW  - DNA Repair
KW  - Genes, BRCA1
KW  - Genes, BRCA2
KW  - Germ-Line Mutation
KW  - High-Throughput Nucleotide Sequencing
KW  - Humans
KW  - Immune Checkpoint Inhibitors
KW  - Indazoles
KW  - Indoles
KW  - Male
KW  - Phthalazines
KW  - Piperazines
KW  - Piperidines
KW  - Platinum Compounds
KW  - Poly(ADP-ribose) Polymerase Inhibitors
KW  - Precision Medicine
KW  - Prognosis
KW  - Prostatic Neoplasms
TI  - Genetic aberrations in DNA repair pathways: a cornerstone of precision oncology in prostate cancer.
TY  - research article
ER  -