TY - JOUR AU - Martín-Fernández, Beatriz AU - Rubio-Navarro, Alfonso AU - Cortegano, Isabel AU - Ballesteros, Sandra AU - Alia, Mario AU - Cannata-Ortiz, Pablo AU - Olivares-Álvaro, Elena AU - Egido, Jesús AU - Andres, Belen de AU - Gaspar, Maria Luisa AU - de Las Heras, Natalia AU - Lahera, Vicente AU - Moreno, Juan Antonio PY - 2016 DO - 10.1371/journal.pone.0145946 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/6986 AB - We aimed to evaluate macrophages heterogeneity and structural, functional and inflammatory alterations in rat kidney by aldosterone + salt administration. The effects of treatment with spironolactone on above parameters were also analyzed. Male Wistar... LA - eng PB - Public Library of Science (PLOS) KW - Aldosterone KW - Animals KW - Fibrosis KW - Inflammation KW - Kidney KW - Kidney Diseases KW - Macrophages KW - Male KW - Mineralocorticoid Receptor Antagonists KW - Rats KW - Rats, Wistar KW - Receptors, Mineralocorticoid KW - Sodium Chloride KW - Spironolactone TI - Aldosterone Induces Renal Fibrosis and Inflammatory M1-Macrophage Subtype via Mineralocorticoid Receptor in Rats TY - journal article ER -