TY  - GEN
AU  - Lopez-Gomez, Antonio
AU  - Clemente, Antonio
AU  - Cunill, Vanesa
AU  - Pons De Ves, Jaime
AU  - Ferrer Balaguer, Juana Maria
PY  - 2018
DO  - 10.1038/s41419-018-1191-8
SN  - 2041-4889
UR  - https://hdl.handle.net/20.500.12105/22598
AB  - Common variable immunodeficiency (CVID) is characterized by an abnormal B cell differentiation to memory and antibody-secreting B cells. The defective functionality of CVID patients' B cells could be the consequence of alterations in apoptosis...
LA  - eng
PB  - Nature Publishing Group
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - B-Lymphocytes
KW  - CD40 Antigens
KW  - Adult
KW  - Common Variable Immunodeficiency
KW  - Gene Expression Regulation
KW  - Humans
KW  - Receptors, Antigen, B-Cell
KW  - Middle Aged
KW  - Lymphocyte Activation
KW  - Interleukins
KW  - Immunologic Memory
KW  - Male
KW  - T-Lymphocytes
KW  - Bcl-2-Like Protein 11
KW  - bcl-X Protein
KW  - Apoptosis
KW  - Female
KW  - bcl-2-Associated X Protein
KW  - Tumor Necrosis Factor Receptor Superfamily, Member 7
TI  - IL-21 and anti-CD40 restore Bcl-2 family protein imbalance in vitro in low-survival CD27(+) B cells from CVID patients
TY  - research article
ER  -