TY - JOUR AU - Zhang, Haiying AU - Freitas, Daniela AU - Kim, Han Sang AU - Fabijanic, Kristina AU - Li, Zhong AU - Chen, Haiyan AU - Mark, Milica Tesic AU - Molina, Henrik AU - Martin, Alberto Benito AU - Bojmar, Linda AU - Fang, Justin AU - Rampersaud, Sham AU - Hoshino, Ayuko AU - Matei, Irina AU - Kenific, Candia M AU - Nakajima, Miho AU - Mutvei, Anders Peter AU - Sansone, Pasquale AU - Buehring, Weston AU - Wang, Huajuan AU - Jimenez, Juan Pablo AU - Cohen-Gould, Leona AU - Paknejad, Navid AU - Brendel, Matthew AU - Manova-Todorova, Katia AU - Magalhães, Ana AU - Ferreira, José Alexandre AU - Osório, Hugo AU - Silva, André M AU - Massey, Ashish AU - Cubillos-Ruiz, Juan R AU - Galletti, Giuseppe AU - Giannakakou, Paraskevi AU - Cuervo, Ana Maria AU - Blenis, John AU - Schwartz, Robert AU - Brady, Mary Sue AU - Peinado, Héctor AU - Bromberg, Jacqueline AU - Matsui, Hiroshi AU - Reis, Celso A AU - Lyden, David PY - 2018 DO - 10.1038/s41556-018-0040-4 UR - http://hdl.handle.net/20.500.12105/17973 AB - The heterogeneity of exosomal populations has hindered our understanding of their biogenesis, molecular composition, biodistribution and functions. By employing asymmetric flow field-flow fractionation (AF4), we identified two exosome subpopulations... LA - eng PB - Nature Publishing Group KW - Nanoparticles KW - Animals KW - Biomarkers KW - Cell Fractionation KW - DNA KW - Energy Metabolism KW - Exosomes KW - Female KW - Glycomics KW - Glycosylation KW - HCT116 Cells KW - Humans KW - Melanoma, Experimental KW - Metabolomics KW - Mice KW - Mice, Inbred C57BL KW - NIH 3T3 Cells KW - Neoplasms KW - PC-3 Cells KW - Phenotype KW - Proteins KW - Proteomics KW - RNA KW - Signal Transduction KW - Tissue Distribution TI - Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation. TY - journal article ER -