TY  - JOUR
AU  - Simón-Carrasco, Lucía
AU  - Graña Castro, Osvaldo
AU  - Salmón, Marina
AU  - Jacob, Harrys K C
AU  - Gutierrez, Alejandro
AU  - Jiménez, Gerardo
AU  - Drosten, Matthias
AU  - Barbacid, Mariano
PY  - 2017
DO  - 10.1101/gad.300244.117
SN  - 0890-9369
UR  - http://hdl.handle.net/20.500.12105/8392
AB  - CIC (also known as Capicua) is a transcriptional repressor negatively regulated by RAS/MAPK signaling. Whereas the functions of Cic have been well characterized in Drosophila, little is known about its role in mammals. CIC is inactivated in a variety...
LA  - eng
PB  - Cold Spring Harbor Laboratory Press
KW  - CIC
KW  - Etv4
KW  - Ras signaling
KW  - T-ALL
KW  - Mouse models
KW  - Adenovirus E1A Proteins
KW  - Alleles
KW  - Animals
KW  - Brain Neoplasms
KW  - Cell Line, Tumor
KW  - Embryonic Development
KW  - Fibroblasts
KW  - Genes, ras
KW  - Humans
KW  - MAP Kinase Signaling System
KW  - Mice
KW  - Mutation
KW  - Oligodendroglioma
KW  - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-ets
KW  - Repressor Proteins
KW  - Transcription, Genetic
TI  - Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma
TY  - journal article
ER  -