TY - GEN AU - García-Argüello, Segundo Francisco AU - Lopez-Lorenzo, Beatriz AU - Cornelissen, Bart AU - Smith, Graham PY - 2020 DO - 10.3390/cancers12082191 UR - http://hdl.handle.net/20.500.12105/18090 AB - Insufficient apoptosis is a recognised hallmark of cancer. A strategy to quantitatively measure apoptosis in vivo would be of immense value in both drug discovery and routine patient management. The first irreversible step in the apoptosis cascade is... LA - eng PB - Multidisciplinary Digital Publishing Institute (MDPI) KW - Positron emission tomography KW - Apoptosis KW - Caspase-3 KW - [18F]ICMT-11 KW - Pyrimidoindolone KW - Michael acceptor KW - Neoplasms KW - Isatin KW - Tomografía de emisión de positrones KW - Caspasa-3 KW - Neoplasias KW - Isatina KW - Caspase 3 KW - Isatin KW - Positron-Emission Tomography KW - Apoptosis Inducing Factor KW - Sulfonamides KW - Neoplasms KW - Drug Discovery KW - Humans TI - Development of [18F]ICMT-11 for Imaging Caspase-3/7 Activity during Therapy-Induced Apoptosis TY - review article ER -