TY  - JOUR
AU  - Meçe, Odeta
AU  - Houbaert, Diede
AU  - Sassano, Maria-Livia
AU  - Durré, Tania
AU  - Maes, Hannelore
AU  - Schaaf, Marco
AU  - More, Sanket
AU  - Ganne, Maarten
AU  - García-Caballero, Melissa
AU  - Borri, Mila
AU  - Verhoeven, Jelle
AU  - Agrawal, Madhur
AU  - Jacobs, Kathryn
AU  - Bergers, Gabriele
AU  - Blacher, Silvia
AU  - Ghesquière, Bart
AU  - Dewerchin, Mieke
AU  - Swinnen, Johan V
AU  - Vinckier, Stefan
AU  - Soengas, MS
AU  - Carmeliet, Peter
AU  - Noël, Agnès
AU  - Agostinis, Patrizia
PY  - 2022
DO  - 10.1038/s41467-022-30490-6
UR  - http://hdl.handle.net/20.500.12105/16062
AB  - Autophagy has vasculoprotective roles, but whether and how it regulates lymphatic endothelial cells (LEC) homeostasis and lymphangiogenesis is unknown. Here, we show that genetic deficiency of autophagy in LEC impairs responses to VEGF-C and...
LA  - eng
PB  - Nature Publishing Group
KW  - Lymphangiogenesis
KW  - Lymphatic Vessels
KW  - Animals
KW  - Autophagy
KW  - Endothelial Cells
KW  - Fatty Acids
KW  - Lipid Droplets
KW  - Mice
KW  - Mitochondria
KW  - Transcription Factors
TI  - Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis.
TY  - journal article
ER  -