TY - GEN AU - Galán, Miguel AU - Hernández-García, Elena AU - Munné, Pablo AU - Redondo-Urzainqui, Ana AU - Cueto, Francisco J AU - Sicilia, Jon AU - Alejano, Sergio Callejas AU - Rey-Martín, M Ascensión AU - Dopazo, Ana AU - Sancho, David AU - Iborra, Salvador PY - 2026 UR - https://hdl.handle.net/20.500.12105/27706 AB - Tyrosine kinases and phosphatases regulate protein phosphorylation and maintain cellular homeostasis. The phosphoprotein tyrosine phosphatase SHP-1 (encoded by the gene) has been proposed as an immune checkpoint in CD8 T cells in preclinical models,... LA - eng PB - FRONTIERS MEDIA KW - CD8+ T cell response KW - SHP-1 KW - conventional type 1 dendritic cells KW - macrophages KW - tumor rejection TI - Loss of SHP-1 in CD11c cells impairs anti-tumor immunity. TY - research article ER -