TY  - JOUR
AU  - Hill, Richard
AU  - Madureira, Patricia A.
AU  - Ferreira, Bibiana
AU  - Baptista, Ines
AU  - Machado, Susana
AU  - Colaco, Laura
AU  - dos Santos, Marta
AU  - Liu, Ningshu
AU  - Dopazo, Ana
AU  - Ugurel, Selma
AU  - Adrienn, Angyal
AU  - Kiss-Toth, Endre
AU  - Isbilen, Murat
AU  - Gure, Ali O.
AU  - Link, Wolfgang
PY  - 2017
DO  - 10.1038/ncomms14687
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/5160
AB  - Intrinsic and acquired resistance to chemotherapy is the fundamental reason for treatment failure for many cancer patients. The identification of molecular mechanisms involved in drug resistance or sensitization is imperative. Here we report that...
LA  - eng
PB  - Nature Publishing Group
KW  - SIGNAL-TRANSDUCTION
KW  - MELANOMA
KW  - PATHWAY
KW  - CELLS
KW  - PHENOTYPE
KW  - SURVIVAL
KW  - AKT/PKB
KW  - MDM2
KW  - FOXO
KW  - P53
TI  - TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT
TY  - journal article
ER  -