TY  - GEN
AU  - González-Cofrade, Laura
AU  - Green, Jack P
AU  - de Las Heras, Beatriz
AU  - Terencio, María Carmen
AU  - Hortelano, Sonsoles
AU  - Brough, David
AU  - Estévez-Braun, Ana
AU  - Ferrándiz, María Luisa
AU  - Cuadrado, Irene
PY  - 2025
DO  - 10.1016/j.bcp.2025.117114
UR  - https://hdl.handle.net/20.500.12105/27384
AB  - Natural products constitute an important resource for drug discovery with hispanolone derivatives recognized as bioactive diterpenes due to their broad therapeutic potential. Dehydroisohispanolone (DIH) is an anti-inflammatory labdane diterpene, that...
LA  - eng
PB  - Elsevier
KW  - ASC
KW  - Dehydroisohispanolone
KW  - Gouty arthritis
KW  - IL-1β
KW  - Macrophages
KW  - NLRP3 inflammasome
KW  - Animals
KW  - Anti-Inflammatory Agents
KW  - Arthritis, Gouty
KW  - Diterpenes
KW  - Humans
KW  - Inflammasomes
KW  - Inflammation
KW  - Macrophages
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - NLR Family, Pyrin Domain-Containing 3 Protein
TI  - Dehydroisohispanolone alleviates NLRP3-driven inflammation in gout arthritis.
TY  - research article
ER  -