TY - JOUR AU - Milani, Gualtiero AU - Budriesi, Roberta AU - Tavazzani, Elisa AU - Cavalluzzi, Maria Maddalena AU - Mattioli, Laura Beatrice AU - Miniero, Daniela Valeria AU - Delre, Pietro AU - Belviso, Benny Danilo AU - Denegri, Marco AU - Cuocci, Corrado AU - Rotondo, Natalie Paola AU - De Palma, Annalisa AU - Gualdani, Roberta AU - Caliandro, Rocco AU - Mangiatordi, Giuseppe Felice AU - Kumawat, Amit AU - Camilloni, Carlo AU - Priori, Silvia G. AU - Lentini, Giovanni PY - 2023 DO - 10.1002/ardp.202300116 UR - http://hdl.handle.net/20.500.12105/16568 AB - Long QT syndrome (LQTS) is a disorder of cardiac electrophysiology resulting in life-threatening arrhythmias; nowadays, only a few drugs are available for the management of LQTS. Focusing our attention on LQT2, one of the most common subtypes of LQTS... LA - eng PB - Wiley KW - Mexiletine KW - Long QT Syndrome KW - Humans KW - Animals KW - Guinea Pigs KW - Molecular Docking Simulation KW - Urea KW - Structure-Activity Relationship KW - Potassium Channels TI - hERG stereoselective modulation by mexiletine-derived ureas: Molecular docking study, synthesis, and biological evaluation. TY - journal article ER -