TY - GEN AU - Lopez-Huertas, Maria Rosa AU - Mateos, Elena AU - Sanchez-Del Cojo, Maria AU - Gómez-Esquer, Francisco AU - Díaz-Gil, Gema AU - Rodriguez‑Mora, Sara AU - Lopez, Juan Antonio AU - Calvo, Enrique AU - Lopez-Campos, Guillermo AU - Alcamí, José AU - Coiras, Mayte PY - 2013 DO - 10.1074/jbc.M112.408294 SN - 0021-9258 UR - http://hdl.handle.net/20.500.12105/6749 AB - HIV-1 replication is efficiently controlled by the regulator protein Tat (101 amino acids) and codified by two exons, although the first exon (1-72 amino acids) is sufficient for this process. Tat can be released to the extracellular medium, acting as... LA - eng KW - CD4-Positive T-Lymphocytes KW - Caspase 3 KW - Caspase 8 KW - Caspase 9 KW - Cytochromes c KW - Exons KW - HIV-1 KW - Humans KW - Jurkat Cells KW - Mitochondria KW - Mutagenesis, Site-Directed KW - NF-kappa B KW - Oligonucleotide Array Sequence Analysis KW - Proteome KW - Proteomics KW - Transfection KW - Fas Receptor KW - tat Gene Products KW - Apoptosis KW - Gene Expression Regulation KW - Human Immunodeficiency Virus TI - The presence of HIV-1 Tat protein second exon delays fas protein-mediated apoptosis in CD4+ T lymphocytes: a potential mechanism for persistent viral production TY - preprint ER -