TY - GEN AU - Díaz-Moreno, María AU - Armenteros, Tomás AU - Gradari, Simona AU - Hortigüela, Rafael AU - García-Corzo, Laura AU - Fontán-Lozano, Ángela AU - Trejo, José Luis AU - Mira, Helena PY - 2018 DO - 10.1073/pnas.1813205115 SN - 0027-8424 UR - http://hdl.handle.net/20.500.12105/9690 AB - Increasing age is the greatest known risk factor for the sporadic late-onset forms of neurodegenerative disorders such as Alzheimer's disease (AD). One of the brain regions most severely affected in AD is the hippocampus, a privileged structure that... LA - eng PB - National Academy of Sciences KW - Alzheimer’s disease KW - BMP signaling KW - Adult neurogenesis KW - Aging KW - Neural stem cells KW - Adult Stem Cells KW - Aging KW - Alzheimer Disease KW - Animals KW - Astrocytes KW - Bone Morphogenetic Protein 6 KW - Carrier Proteins KW - Cell Differentiation KW - Disease Models, Animal KW - Hippocampus KW - Humans KW - Injections, Intraventricular KW - Male KW - Mice KW - Mice, Transgenic KW - Neural Stem Cells KW - Neurogenesis KW - Neurons KW - Neuroprotective Agents KW - Signal Transduction TI - Noggin rescues age-related stem cell loss in the brain of senescent mice with neurodegenerative pathology TY - research article ER -