TY  - JOUR
AU  - Hewitt, Graeme
AU  - Borel, Valerie
AU  - Segura-Bayona, Sandra
AU  - Takaki, Tohru
AU  - Ruis, Phil
AU  - Bellelli, Roberto
AU  - Lehmann, Laura C
AU  - Sommerova, Lucia
AU  - Vancevska, Aleksandra
AU  - Tomas-Loba, Antonia
AU  - Zhu, Kang
AU  - Cooper, Christopher
AU  - Fugger, Kasper
AU  - Patel, Harshil
AU  - Goldstone, Robert
AU  - Schneider-Luftman, Deborah
AU  - Herbert, Ellie
AU  - Stamp, Gordon
AU  - Brough, Rachel
AU  - Pettitt, Stephen
AU  - Lord, Christopher J
AU  - West, Stephen C
AU  - Ahel, Ivan
AU  - Ahel, Dragana
AU  - Chapman, J Ross
AU  - Deindl, Sebastian
AU  - Boulton, Simon J
PY  - 2021
DO  - 10.1016/j.molcel.2020.12.006
SN  - 1097-2765
UR  - http://hdl.handle.net/20.500.12105/13347
AB  - Chromatin is a barrier to efficient DNA repair, as it hinders access and processing of certain DNA lesions. ALC1/CHD1L is a nucleosome-remodeling enzyme that responds to DNA damage, but its precise function in DNA repair remains unknown. Here we...
LA  - eng
PB  - Cell Press
TI  - Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
TY  - journal article
ER  -