TY - GEN AU - Hurtado-Guerrero, Isaac AU - Pinto-Medel, María Jesús AU - Urbaneja, Patricia AU - Rodriguez-Bada, Jose Luis AU - León, Antonio AU - Guerrero, Miguel AU - Fernández, Óscar AU - Leyva, Laura AU - Oliver-Martos, Begoña PY - 2017 DO - 10.1371/journal.pone.0170031 UR - http://hdl.handle.net/20.500.12105/17283 AB - Interferon beta (IFNß) is a common treatment used for multiple sclerosis (MS) which acts through the activation of the JAK-STAT pathway. However, this therapy is not always effective and currently there are no reliable biomarkers to predict... LA - eng PB - Public Library of Science (PLOS) KW - Biomarcadores KW - Citometría de flujo KW - Humanos KW - Leucocitos mononucleares KW - Monocitos KW - Esclerosis múltiple KW - Fenotipo KW - Factor de Transcripción STAT1 KW - Factor de Transcripción STAT2 KW - Resultado del tratamiento KW - Biomarkers KW - Flow Cytometry KW - Humans KW - Interferon beta-1a KW - Interferon-beta KW - Leukocytes, Mononuclear KW - Monocytes KW - Multiple Sclerosis KW - Phenotype KW - STAT1 Transcription Factor KW - STAT2 Transcription Factor KW - Treatment Outcome TI - Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß TY - research article ER -