TY  - JOUR
AU  - van der Lelij, Petra
AU  - Lieb, Simone
AU  - Jude, Julian
AU  - Wutz, Gordana
AU  - Santos, Catarina P
AU  - Falkenberg, Katrina
AU  - Schlattl, Andreas
AU  - Ban, Jozef
AU  - Schwentner, Raphaela
AU  - Hoffmann, Thomas
AU  - Kovar, Heinrich
AU  - Real Arribas, Francisco
AU  - Waldman, Todd
AU  - Pearson, Mark A
AU  - Kraut, Norbert
AU  - Peters, Jan-Michael
AU  - Zuber, Johannes
AU  - Petronczki, Mark
PY  - 2017
DO  - 10.7554/eLife.26980
SN  - 2050-084X
UR  - http://hdl.handle.net/20.500.12105/7110
AB  - Recent genome analyses have identified recurrent mutations in the cohesin complex in a wide range of human cancers. Here we demonstrate that the most frequently mutated subunit of the cohesin complex, STAG2, displays a strong synthetic lethal...
LA  - eng
PB  - eLife Sciences Publications
KW  - Cancer biology
KW  - Cell biology
KW  - Cell division
KW  - Chromosomes
KW  - Cohesin
KW  - Genetic interaction
KW  - Human
KW  - Mitosis
KW  - Synthetic lethality
KW  - Antigens, Nuclear
KW  - Cell Division
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Humans
KW  - Nuclear Proteins
KW  - Synthetic Lethal Mutations
TI  - Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts
TY  - journal article
ER  -