TY  - GEN
AU  - García-Alonso, Sara
AU  - Mesa, Pablo
AU  - Ovejero, Laura de la Puente
AU  - Aizpurua, Gonzalo
AU  - Lechuga, Carmen G
AU  - Zarzuela, Eduardo
AU  - Santiveri, Clara M
AU  - Sanclemente, Manuel
AU  - Muñoz, Javier
AU  - Musteanu, Mónica
AU  - Campos-Olivas, Ramón
AU  - Martínez-Torrecuadrada, Jorge
AU  - Barbacid, Mariano
AU  - Montoya, Guillermo
PY  - 2022
UR  - https://hdl.handle.net/20.500.12105/26791
AB  - RAF kinases are RAS-activated enzymes that initiate signaling through the MAPK cascade to control cellular proliferation, differentiation, and survival. Here, we describe the structure of the full-length RAF1 protein in complex with HSP90 and CDC37...
LA  - eng
PB  - Cell Press
KW  - MAPK signaling
KW  - RAF kinases
KW  - RAF1
KW  - cancer
KW  - cryo-EM
TI  - Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.
TY  - research article
ER  -