TY  - JOUR
AU  - Djouder, Nabil
AU  - Metzler, Stefan Christian
AU  - Schmidt, Alexander
AU  - Wirbelauer, Christiane
AU  - Gstaiger, Matthias
AU  - Aebersold, Ruedi
AU  - Hess, Daniel
AU  - Krek, Wilhelm
PY  - 2007
DO  - 10.1016/j.molcel.2007.08.010
SN  - 1097-2765
UR  - http://hdl.handle.net/20.500.12105/17541
AB  - S6 kinase 1 (S6K1) acts to integrate nutrient and growth factor signals to promote cell growth but also cell survival as a mitochondria-tethered protein kinase that phosphorylates and inactivates the proapoptotic molecule BAD. Here we report that the...
LA  - eng
PB  - Elsevier
KW  - Amino Acid Sequence
KW  - Animals
KW  - Apoptosis
KW  - Cell Line
KW  - Cell Survival
KW  - Feedback, Physiological
KW  - Humans
TI  - S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling.
TY  - journal article
ER  -