TY - JOUR AU - Garcia-Pavia, Pablo AU - Aus dem Siepen, Fabian AU - Donal, Erwan AU - Lairez, Olivier AU - van der Meer, Peter AU - Kristen, Arnt V AU - Mercuri, Michele F AU - Michalon, Aubin AU - Frost, Robert J A AU - Grimm, Jan AU - Nitsch, Roger M AU - Hock, Christoph AU - Kahr, Peter C AU - Damy, Thibaud PY - 2023 DO - 10.1056/NEJMoa2303765 UR - http://hdl.handle.net/20.500.12105/19299 AB - BACKGROUNDTransthyretin amyloid (ATTR) cardiomyopathy is a progressive and fatal disease caused by misfolded transthyretin. Despite advances in slowing disease progression, there is no available treatment that depletes ATTR from the heart for the... LA - eng PB - Massachusetts Medical Society KW - Amyloid Neuropathies, Familial KW - Antibodies KW - Cardiomyopathies KW - Heart Failure KW - Recombinant Proteins KW - Humans KW - Magnetic Resonance Imaging KW - Prealbumin KW - Double-Blind Method KW - Chronic Disease KW - Infusions, Intravenous TI - Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid. TY - journal article ER -