TY - JOUR AU - Lipskaia, Larissa AU - Breau, Marielle AU - Cayrou, Christelle AU - Churikov, Dmitri AU - Braud, Laura AU - Jacquet, Juliette AU - Born, Emmanuelle AU - Fouillade, Charles AU - Curras-Alonso, Sandra AU - Bauwens, Serge AU - Jourquin, Frederic AU - Fiore, Frederic AU - Castellano, Rémy AU - Josselin, Emmanuelle AU - Sánchez-Ferrer, Carlota AU - Giovinazzo, Giovanna AU - Lachaud, Christophe AU - Gilson, Eric AU - Flores, Ignacio AU - Londono-Vallejo, Arturo AU - Adnot, Serge AU - Géli, Vincent PY - 2024 DO - 10.1038/s44319-023-00041-1 UR - http://hdl.handle.net/20.500.12105/20039 AB - Lung diseases develop when telomeres shorten beyond a critical point. We constructed a mouse model in which the catalytic subunit of telomerase (mTert), or its catalytically inactive form (mTertCI), is expressed from the p21Cdkn1a locus. Expression of... LA - eng PB - Wiley KW - Pulmonary Emphysema KW - Microvascular Rarefaction KW - Emphysema KW - Telomerase KW - Mice KW - Animals KW - Telomere Shortening TI - mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema. TY - journal article ER -