TY - GEN AU - Robles-Díaz, Mercedes AU - Lucena, M Isabel AU - Kaplowitz, Neil AU - Stephens, Camilla AU - Medina-Cáliz, Inmaculada AU - González-Jiménez, Andrés AU - Ulzurrun, Eugenia AU - González, Ana F AU - Fernández, M Carmen AU - Romero-Gómez, Manuel AU - Jiménez-Pérez, Miguel AU - Bruguera, Miguel AU - Prieto, Martín AU - Bessone, Fernando AU - Hernández, Nelia AU - Arrese, Marco AU - Andrade, Raúl J PY - 2014 DO - 10.1053/j.gastro.2014.03.050 SN - 0016-5085 UR - http://hdl.handle.net/20.500.12105/17072 AB - BACKGROUND & AIMS: Hy's Law, which states that hepatocellular drug-induced liver injury (DILI) with jaundice indicates a serious reaction, is used widely to determine risk for acute liver failure (ALF). We aimed to optimize the definition of Hy's Law... LA - eng PB - WB Saunders KW - Idiosyncratic Hepatotoxicity KW - Prognostic Risk Factor KW - Prediction KW - Progression KW - Comorbilidad KW - Enfermedad hepática inducida por drogas KW - Ictericia KW - Fallo hepático agudo KW - Valor predictivo de las pruebas KW - Factores de riesgo KW - Sensibilidad y especificidad KW - Factores sexuales KW - Alanina transaminasa KW - Algoritmos KW - Bilirrubina KW - Marcadores biológicos KW - Niños KW - Adult TI - Use of Hy's law and a new composite algorithm to predict acute liver failure in patients with drug-induced liver injury. TY - research article ER -