TY - JOUR AU - Thambyrajah, Roshana AU - Maqueda, Maria AU - Neo, Wen Hao AU - Imbach, Kathleen AU - Guillén, Yolanda AU - Grases, Daniela AU - Fadlullah, Zaki AU - Gambera, Stefano AU - Matteini, Francesca AU - Wang, Xiaonan AU - Calero-Nieto, Fernando J AU - Esteller, Manel AU - Florian, Maria Carolina AU - Porta, Eduard AU - Benedito, Rui AU - Göttgens, Berthold AU - Lacaud, Georges AU - Espinosa, Lluis AU - Bigas, Anna PY - 2024 DO - 10.1038/s41467-024-45716-y UR - http://hdl.handle.net/20.500.12105/20320 AB - Hematopoietic stem cells (HSCs) develop from the hemogenic endothelium (HE) in the aorta- gonads-and mesonephros (AGM) region and reside within Intra-aortic hematopoietic clusters (IAHC) along with hematopoietic progenitors (HPC). The signalling... LA - eng PB - Nature Publishing Group KW - Receptor, Notch1 KW - Hematopoietic Stem Cells KW - Cell Differentiation KW - Aorta KW - Arteries KW - Mesonephros KW - Gonads TI - Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate. TY - journal article ER -