TY - JOUR AU - Kangsamaksin, Thaned AU - Murtomaki, Aino AU - Kofler, Natalie M AU - Cuervo, Henar AU - Chaudhri, Reyhaan A AU - Tattersall, Ian W AU - Rosenstiel, Paul E AU - Shawber, Carrie J AU - Kitajewski, Jan PY - 2015 DO - 10.1158/2159-8290.CD-14-0650 UR - http://hdl.handle.net/20.500.12105/17213 AB - UNLABELLEDA proangiogenic role for Jagged (JAG)-dependent activation of NOTCH signaling in the endothelium has yet to be described. Using proteins that encoded different NOTCH1 EGF-like repeats, we identified unique regions of Delta-like ligand... LA - eng PB - American Association for Cancer Research (AACR) KW - Angiogenesis Inhibitors KW - Animals KW - Female KW - Humans KW - Immunoglobulin Fc Fragments TI - NOTCH decoys that selectively block DLL/NOTCH or JAG/NOTCH disrupt angiogenesis by unique mechanisms to inhibit tumor growth. TY - journal article ER -