TY - JOUR AU - Rivera-Torres, Jose AU - Guzman-Martinez, Gabriela AU - Villa-Bellosta, Ricardo AU - Orbe, Josune AU - Gonzalez-Gomez, Cristina AU - Serrano, Manuel AU - Díez, Javier AU - Andres, Vicente AU - Maraver, Antonio PY - 2015 DO - 10.1097/HJH.0000000000000463 SN - 0263-6352 UR - http://hdl.handle.net/20.500.12105/7922 AB - OBJECTIVE: The Notch pathway has been linked to pulmonary hypertension, but its role in systemic hypertension and, in particular in left ventricular hypertrophy (LVH), remains poorly understood. The main objective of this work was to analyse the... LA - eng PB - Lippincott Williams & Wilkins (LWW) KW - Amyloid Precursor Protein Secretases KW - Angiotensin II KW - Animals KW - Blood Pressure KW - Cardiomegaly KW - Cells, Cultured KW - Dibenzazepines KW - Disease Models, Animal KW - Drug Evaluation, Preclinical KW - Humans KW - Hypertension KW - Hypertrophy, Left Ventricular KW - Male KW - Mice KW - Middle Aged KW - Muscle, Smooth, Vascular KW - Signal Transduction TI - Targeting γ-secretases protect against angiotensin II-induced cardiac hypertrophy TY - journal article ER -