TY - JOUR AU - Calvet-Mirabent, Marta AU - Sánchez-Cerrillo, Ildefonso AU - Martín-Cófreces, Noa AU - Martínez-Fleta, Pedro AU - de la Fuente, Hortensia AU - Tsukalov, Ilya AU - Delgado-Arévalo, Cristina AU - Calzada, María José AU - de Los Santos, Ignacio AU - Sanz, Jesús AU - García-Fraile, Lucio AU - Sánchez-Madrid, Francisco AU - Alfranca, Arantzazu AU - Muñoz-Fernández, María Ángeles AU - Buzón, Maria J AU - Martín-Gayo, Enrique PY - 2022 DO - 10.1016/j.ebiom.2022.104090 UR - http://hdl.handle.net/20.500.12105/15644 AB - Dysfunction of CD8+ T cells in people living with HIV-1 (PLWH) receiving anti-retroviral therapy (ART) has restricted the efficacy of dendritic cell (DC)-based immunotherapies against HIV-1. Heterogeneous immune exhaustion and metabolic states of CD8+... LA - eng PB - Elsevier KW - HIV Infections KW - HIV-1 KW - Anti-Retroviral Agents KW - CD4-Positive T-Lymphocytes KW - CD8-Positive T-Lymphocytes KW - Dendritic Cells KW - Humans TI - Antiretroviral therapy duration and immunometabolic state determine efficacy of ex vivo dendritic cell-based treatment restoring functional HIV-specific CD8+ T cells in people living with HIV. TY - journal article ER -