TY - JOUR AU - Hurtado Villarejo, Begoña AU - Trakala, Marianna AU - Ximenez-Embun, Pilar AU - El Bakkali, Aicha AU - Partida, David AU - Sanz-Castillo, Belén AU - Alvarez Fernandez, Monica AU - Maroto, María AU - Sánchez-Martínez, Ruth AU - Martinez Garcia, Maria Dolores AU - Muoz Peralta, Javier AU - García de Frutos, Pablo AU - Malumbres Martinez, Marcos PY - 2018 DO - 10.1172/JCI121876 SN - 1558-8238 UR - http://hdl.handle.net/20.500.12105/6505 AB - MASTL, a Ser/Thr kinase that inhibits PP2A-B55 complexes during mitosis, is mutated in autosomal dominant thrombocytopenia. However, the connections between the cell cycle machinery and this human disease remain unexplored. We report here that,... LA - eng PB - American Society for Clinical Investigation (ASCI) KW - Cell Biology KW - Cell cycle KW - Hematology KW - Phosphoprotein phosphatases KW - Thrombosis TI - Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeleton dynamics in platelets TY - journal article ER -