TY  - JOUR
AU  - Sáenz de Urturi, Diego
AU  - Buqué, Xabier
AU  - Porteiro, Begoña
AU  - Folgueira, Cintia
AU  - Mora, Alfonso
AU  - Delgado, Teresa C
AU  - Prieto-Fernández, Endika
AU  - Olaizola, Paula
AU  - Gómez-Santos, Beatriz
AU  - Apodaka-Biguri, Maider
AU  - González-Romero, Francisco
AU  - Nieva-Zuluaga, Ane
AU  - Ruiz de Gauna, Mikel
AU  - Goikoetxea-Usandizaga, Naroa
AU  - García-Rodríguez, Juan Luis
AU  - Gutierrez de Juan, Virginia
AU  - Aurrekoetxea, Igor
AU  - Montalvo-Romeral, Valle
AU  - Novoa, Eva M
AU  - Martín-Guerrero, Idoia
AU  - Varela-Rey, Marta
AU  - Bhanot, Sanjay
AU  - Lee, Richard
AU  - Banales, Jesus M
AU  - Syn, Wing-Kin
AU  - Sabio, Guadalupe
AU  - Martínez-Chantar, María L
AU  - Nogueiras, Rubén
AU  - Aspichueta, Patricia
PY  - 2022
DO  - 10.1038/s41467-022-28749-z
UR  - http://hdl.handle.net/20.500.12105/15706
AB  - Altered methionine metabolism is associated with weight gain in obesity. The methionine adenosyltransferase (MAT), catalyzing the first reaction of the methionine cycle, plays an important role regulating lipid metabolism. However, its role in...
LA  - eng
PB  - Nature Publishing Group
KW  - Adipose Tissue, Brown
KW  - Insulin Resistance
KW  - Methionine Adenosyltransferase
KW  - Obesity
KW  - Oligonucleotides, Antisense
KW  - Animals
KW  - Energy Metabolism
KW  - Liver
KW  - Mice
KW  - NF-E2-Related Factor 2
TI  - Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis.
TY  - journal article
ER  -