TY - JOUR AU - González-Corpas, Ana AU - Cabezudo, Sofía AU - López-Perrote, Andrés AU - Degliesposti, Gianluca AU - Zarzuela, Eduardo AU - Skehel, J Mark AU - Muñoz, Javier AU - Serna, Marina AU - Llorca Blanco, Oscar Antonio PY - 2022 DO - 10.1093/nar/gkab1267 UR - http://hdl.handle.net/20.500.12105/13716 AB - Biogenesis of the U5 small nuclear ribonucleoprotein (snRNP) is an essential and highly regulated process. In particular, PRPF8, one of U5 snRNP main components, requires HSP90 working in concert with R2TP, a cochaperone complex containing RUVBL1 and... LA - eng PB - Oxford University Press KW - ATPases Associated with Diverse Cellular Activities KW - Carrier Proteins KW - DNA Helicases KW - HEK293 Cells KW - Humans KW - Phosphoproteins KW - Protein Binding KW - RNA Precursors KW - RNA Splicing KW - RNA, Messenger KW - RNA-Binding Proteins TI - CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8. TY - journal article ER -