TY - GEN AU - Medina-Vera, Dina AU - Navarro, Juan Antonio AU - Rivera, Patricia AU - Rosell-Valle, Cristina AU - Gutiérrez-Adán, Alfonso AU - Sanjuan, Carlos AU - López-Gambero, Antonio Jesús AU - Tovar, Rubén AU - Suárez, Juan AU - Pavón, Francisco Javier AU - Baixeras, Elena AU - Decara, Juan AU - Rodríguez de Fonseca, Fernando PY - 2022 DO - 10.1111/bph.15907 UR - http://hdl.handle.net/20.500.12105/18715 AB - Recent evidence links brain insulin resistance with neurodegenerative diseases, where hyperphosphorylated tau protein contributes to neuronal cell death. In the present study, we aimed to evaluate if d-pinitol inositol, which acts as an insulin... LA - eng KW - Akt KW - CDK5 KW - d-pinitol KW - insulin KW - tau phosphorylation KW - tauopathy KW - Animals KW - Cyclin-Dependent Kinase 5 KW - Glycogen Synthase Kinase 3 KW - Inositol KW - Insulins KW - Leptin KW - Mice KW - Phosphorylation KW - Rats KW - Rats, Wistar KW - Rats, Zucker KW - Tauopathies KW - tau Proteins TI - d-Pinitol promotes tau dephosphorylation through a cyclin-dependent kinase 5 regulation mechanism: A new potential approach for tauopathies? TY - research article ER -