TY - GEN AU - Garcia-Barbazan, Irene AU - Torres-Cano, Alba AU - Garcia-Rodas, Rocio AU - Sachse, Martin AU - Luque, Daniel AU - MegĂ­as, Diego AU - Zaragoza, Oscar PY - 2024 DO - 10.1128/mbio.02549-23 UR - http://hdl.handle.net/20.500.12105/16821 AB - Cryptococcus neoformans is an excellent model to investigate fungal pathogenesis. This yeast can produce "titan cells," which are cells of an abnormally larger size that contribute to the persistence of the yeast in the host. In this work, we have... LA - eng PB - American Society for Microbiology (ASM) KW - Cryptococcus neoformans KW - Mitochondria KW - Off-patent drug repurposing KW - Reactive oxygen species KW - Titan-like cells TI - Accumulation of endogenous free radicals is required to induce titan-like cell formation in Cryptococcus neoformans TY - research article ER -