TY  - JOUR
AU  - Alvarez, Silvia
AU  - Diaz, Marcos
AU  - Flach, Johanna
AU  - Rodriguez-Acebes, Sara
AU  - Lopez-Contreras, Andres J.
AU  - Martinez, Dolores
AU  - Cañamero, Marta
AU  - Fernandez-Capetillo, Oscar
AU  - Isern, Joan
AU  - Passegue, Emmanuelle
AU  - Mendez, Juan
PY  - 2015
DO  - 10.1038/ncomms9548
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/5385
AB  - Replicative stress during embryonic development influences ageing andpredisposition to disease in adults. A protective mechanism againstreplicative stress is provided by the licensing of thousands of originsin G1 that are not necessarily activated in...
LA  - eng
PB  - Nature Publishing Group
KW  - DNA-REPLICATION
KW  - DORMANT ORIGINS
KW  - EXCESS MCM2-7
KW  - IN-VIVO
KW  - DAMAGE
KW  - CYCLE
KW  - CANCER
KW  - LOCUS
KW  - DIFFERENTIATION
KW  - SPECIFICATION
TI  - Replication stress caused by low MCM expression limits fetalerythropoiesis and hematopoietic stem cell functionality
TY  - journal article
ER  -