TY  - GEN
AU  - Murga, Matilde
AU  - Lopez-Pernas, Gema
AU  - Soliva, Robert
AU  - Fueyo-Marcos, Elena
AU  - Amor, Corina
AU  - Faustino, Ignacio
AU  - Serna, Marina
AU  - Serrano, Alicia G
AU  - Díaz, Lucía
AU  - Martínez, Sonia
AU  - Blanco-Aparicio, Carmen
AU  - Antón, Marta Elena
AU  - Seashore-Ludlow, Brinton
AU  - Pastor Fernandez, Joaquin
AU  - Jafari, Rozbeh
AU  - Lafarga, Miguel
AU  - Llorca Blanco, Oscar Antonio
AU  - Orozco, Modesto
AU  - Fernandez-Capetillo, Oscar
PY  - 2024
UR  - https://hdl.handle.net/20.500.12105/25882
AB  - SETD8 is a methyltransferase that is overexpressed in several cancers, which monomethylates H4K20 as well as other non-histone targets such as PCNA or p53. We here report novel SETD8 inhibitors, which were discovered while trying to identify chemicals...
LA  - eng
PB  - Nature Publishing Group
KW  - METHYLTRANSFERASE SETD8
KW  - ACCURATE DOCKING
KW  - 53BP1
KW  - DATABASE
KW  - GLIDE
KW  - IDENTIFICATION
KW  - RECOGNITION
KW  - POTENTIALS
KW  - PR-SET7
KW  - DRUG
TI  - SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis.
TY  - research article
ER  -