TY - JOUR AU - González-Reyes, L AU - Ruiz-Argüello, M B AU - Garcia-Barreno, Blanca AU - Calder, L AU - López, J A AU - Albar, Juan Pablo AU - Skehel, J J AU - Wiley, D C AU - Melero, Jose Antonio PY - 2001 DO - 10.1073/pnas.151098198 SN - 0027-8424 UR - http://hdl.handle.net/20.500.12105/9952 AB - Preparations of purified full-length fusion (F) protein of human respiratory syncytial virus (HRSV) expressed in recombinant vaccinia-F infected cells, or of an anchorless mutant (F(TM(-))) lacking the C-terminal 50 amino acids secreted from... LA - eng PB - National Academy of Sciences KW - Amino Acid Motifs KW - Amino Acid Sequence KW - Animals KW - Cell Line KW - Cricetinae KW - Cytopathogenic Effect, Viral KW - Endopeptidases KW - Giant Cells KW - Humans KW - Kidney KW - Membrane Fusion KW - Mesocricetus KW - Microscopy, Electron KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Protein Conformation KW - Protein Precursors KW - Recombinant Fusion Proteins KW - Respiratory Syncytial Viruses KW - Structure-Activity Relationship KW - Viral Fusion Proteins KW - Viral Proteins KW - Protein Processing, Post-Translational TI - Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion TY - journal article ER -