TY  - JOUR
AU  - Ecker, Simone
AU  - Chen, Lu
AU  - Pancaldi, Vera
AU  - Bagger, Frederik O
AU  - Fernández, José María
AU  - Carrillo-de-Santa-Pau, Enrique
AU  - Juan, David
AU  - Mann, Alice L
AU  - Watt, Stephen
AU  - Casale, Francesco Paolo
AU  - Sidiropoulos, Nikos
AU  - Rapin, Nicolas
AU  - Merkel, Angelika
AU  - Stunnenberg, Hendrik G
AU  - Stegle, Oliver
AU  - Frontini, Mattia
AU  - Downes, Kate
AU  - Pastinen, Tomi
AU  - Kuijpers, Taco W
AU  - Rico, Daniel
AU  - Valencia, Alfonso
AU  - Beck, Stephan
AU  - Soranzo, Nicole
AU  - Paul, Dirk S
PY  - 2017
DO  - 10.1186/s13059-017-1156-8
SN  - 1474-760X
UR  - http://hdl.handle.net/20.500.12105/7240
AB  - BACKGROUND: A healthy immune system requires immune cells that adapt rapidly to environmental challenges. This phenotypic plasticity can be mediated by transcriptional and epigenetic variability. RESULTS: We apply a novel analytical approach to...
LA  - eng
PB  - BioMed Central (BMC)
KW  - DNA methylation
KW  - Differential variability
KW  - Gene expression
KW  - Heterogeneity
KW  - Immune cells
KW  - Monocytes
KW  - Neutrophils
KW  - Phenotypic plasticity
KW  - T cells
KW  - Cluster Analysis
KW  - CpG Islands
KW  - DNA Methylation
KW  - Female
KW  - Gene Expression Profiling
KW  - Gene Regulatory Networks
KW  - Genetic Variation
KW  - Humans
KW  - Immune System
KW  - Male
KW  - Neutrophils
KW  - Organ Specificity
KW  - Sex Factors
KW  - Epigenesis, Genetic
KW  - Gene Expression Regulation
KW  - Genome-Wide Association Study
KW  - Transcription, Genetic
TI  - Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types
TY  - journal article
ER  -