TY  - GEN
AU  - Stephens, Camilla
AU  - López-Nevot, Miguel-Ángel
AU  - Ruiz-Cabello, Francisco
AU  - Ulzurrun, Eugenia
AU  - Soriano, Germán
AU  - Romero-Gómez, Manuel
AU  - Moreno-Casares, Antonia
AU  - Lucena, M Isabel
AU  - Andrade, Raul J
PY  - 2013
DO  - 10.1371/journal.pone.0068111
UR  - http://hdl.handle.net/20.500.12105/17053
AB  - BACKGROUND AND AIM: The genotype-phenotype interaction in drug-induced liver injury (DILI) is a subject of growing interest. Previous studies have linked amoxicillin-clavulanate (AC) hepatotoxicity susceptibility to specific HLA alleles. In this study...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Combinación Amoxicilina-Clavulanato de Potasio
KW  - Enfermedad Hepática Inducida por Drogas
KW  - Predisposición Genética a la Enfermedad
KW  - Haplotipos
KW  - Fenotipo
KW  - Inmunidad Adaptativa
KW  - Antibacterianos
KW  - Genes Clase I del Complejo de Histocompatibilidad (MHC)
KW  - Genes Clase II del Complejo de Histocompatibilidad (MHC)
KW  - Antígenos HLA-A
KW  - Antígenos HLA-DQ
KW  - Antígenos HLA-DR
KW  - Cadenas beta de HLA-DR
KW  - Factores de riesgo
KW  - España
KW  - Amoxicillin-Potassium Clavulanate Combination
KW  - Drug-Induced Liver Injury
KW  - Genetic Predisposition to Disease
KW  - Haplotypes
KW  - Phenotype
KW  - Adaptive Immunity
KW  - Anti-Bacterial Agents
KW  - Genes, MHC Class I
KW  - Genes, MHC Class II
KW  - HLA-A Antigens
KW  - HLA-DQ Antigens
KW  - HLA-DR Antigens
KW  - HLA-DR beta-Chains
KW  - Risk Factors
KW  - Spain
TI  - HLA Alleles Influence the Clinical Signature of Amoxicillin-Clavulanate Hepatotoxicity.
TY  - research article
ER  -