TY - GEN AU - Corman, Alba AU - Kanellis, Dimitris C AU - Michalska, Patrycja AU - Häggblad, Maria AU - Lafarga, Vanesa AU - Bartek, Jiri AU - Carreras-Puigvert, Jordi AU - Fernandez-Capetillo, Oscar PY - 2021 UR - https://hdl.handle.net/20.500.12105/26084 AB - We here conducted an image-based chemical screen to evaluate how medically approved drugs, as well as drugs that are currently under development, influence overall translation levels. None of the compounds up-regulated translation, which could be due... LA - eng KW - PROTEIN-SYNTHESIS KW - DISCOVERY KW - EXPRESSION KW - SOFTWARE KW - LEUKEMIA KW - GROWTH KW - CANCER KW - POTENT KW - CELLS KW - MYC TI - A chemical screen for modulators of mRNA translation identifies a distinct mechanism of toxicity for sphingosine kinase inhibitors. TY - research article ER -