TY - JOUR AU - Molina-Sanchez, Pedro AU - del Campo, Lara AU - Esteban, Vanesa AU - Rius, Cristina AU - Chevre, Raphael AU - Fuster, Jose J. AU - Ferrer, Mercedes AU - Redondo, Juan Miguel AU - Andres, Vicente PY - 2018 DO - 10.1016/j.yjmcc.2018.01.010 SN - 0022-2828 UR - http://hdl.handle.net/20.500.12105/6491 AB - Phosphorylation at serine 10 (S10) is the major posttranslational modification of the tumor suppressor p27, and is reduced in both human and mouse atherosclerosis. Moreover, a lack of p27-phospho-S10 in apolipoprotein E-null mice (apoE-/-) leads to... LA - eng PB - Elsevier KW - Aneurysm KW - Cox-2 KW - Endothelial cell KW - Vascular contractility KW - p27 KW - p27 phosphorylation at serine 10 TI - Defective p27 phosphorylation at serine 10 affects vascular reactivity and increases abdominal aortic aneurysm development via Cox-2 activation TY - journal article ER -