TY  - JOUR
AU  - Santos, Catarina P
AU  - Lapi, Eleonora
AU  - Martínez de Villarreal, Jaime
AU  - Álvaro-Espinosa, Laura
AU  - Fernández-Barral, Asunción
AU  - Barbáchano, Antonio
AU  - Dominguez, Orlando
AU  - Laughney, Ashley M
AU  - Megias Vazquez, Diego
AU  - Muñoz, Alberto
AU  - Real Arribas, Francisco
PY  - 2019
DO  - 10.1038/s41467-019-12307-1
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/9319
AB  - Understanding urothelial stem cell biology and differentiation has been limited by the lack of methods for their unlimited propagation. Here, we establish mouse urothelial organoids that can be maintained uninterruptedly for >1 year. Organoid growth...
LA  - eng
PB  - Nature Publishing Group
KW  - Animals
KW  - Cell Differentiation
KW  - Cell Line, Tumor
KW  - Epidermal Growth Factor
KW  - Gene Expression Profiling
KW  - Gene Ontology
KW  - Gene Regulatory Networks
KW  - Humans
KW  - Integrin alpha6
KW  - Mice, 129 Strain
KW  - Mice, Inbred C57BL
KW  - Mice, Nude
KW  - Mice, Transgenic
KW  - Organoids
KW  - Receptors, Notch
KW  - Single-Cell Analysis
KW  - Stem Cells
KW  - Urothelium
TI  - Urothelial organoids originating from Cd49fhigh mouse stem cells display Notch-dependent differentiation capacity
TY  - journal article
ER  -