TY  - GEN
AU  - Perez-Luz, Sara
AU  - Lalchandani, Jaanam
AU  - Matamala, Nerea
AU  - Barrero, Maria
AU  - Gil-Martín, Sara
AU  - Ramos-Del Saz, Sheila
AU  - Varona Fernandez, Sarai
AU  - Monzon-Fernandez, Sara
AU  - Cuesta de la Plaza, Isabel
AU  - Justo, Iago
AU  - Marcacuzco, Alberto
AU  - Hierro, Loreto
AU  - Garfia, Cristina
AU  - Gomez-Mariano, Gema Maria
AU  - Janciauskiene, Sabina
AU  - Martinez-Delgado, Beatriz
PY  - 2023
DO  - 10.3390/ijms241512472
UR  - http://hdl.handle.net/20.500.12105/16353
AB  - Different mutations in the SERPINA1 gene result in alpha-1 antitrypsin (AAT) deficiency and in an increased risk for the development of liver diseases. More than 90% of severe deficiency patients are homozygous for Z (Glu342Lys) mutation. This...
LA  - eng
PB  - Multidisciplinary Digital Publishing Institute (MDPI)
KW  - AAT aggregates
KW  - Alpha-1 antitrypsin (AAT)
KW  - Alpha-1 antitrypsin deficiency (AATD)
KW  - Lipid accumulation
KW  - Liver organoids
KW  - alpha 1-Antitrypsin Deficiency
KW  - alpha 1-Antitrypsin
KW  - Humans
KW  - Lipids
KW  - Liver Cirrhosis
KW  - Organoids
TI  - Quantitative Lipid Profiling Reveals Major Differences between Liver Organoids with Normal Pi*M and Deficient Pi*Z Variants of Alpha-1-antitrypsin.
TY  - research article
ER  -