TY - JOUR AU - Ruiz, Susana AU - Domenech, Mirian AU - Antequera, María Luisa AU - García, Pedro AU - García, Ernesto AU - Corsini, Bruno AU - Aguinagalde, Leire AU - Fenoll, Asuncion AU - Yuste, Jose Enrique PY - 2016 DO - 10.1016/j.vaccine.2016.11.001 UR - http://hdl.handle.net/20.500.12105/10341 AB - The cell wall glucosaminidase LytB of Streptococcus pneumoniae is a surface exposed protein involved in daughter cell separation, biofilm formation and contributes to different aspects of the pathogenesis process. In this study we have characterized... LA - eng PB - Elsevier KW - Phagocytosis KW - Adjuvants, Immunologic KW - Aluminum Hydroxide KW - Animals KW - Antibodies, Bacterial KW - Complement System Proteins KW - Disease Models, Animal KW - Enzyme-Linked Immunosorbent Assay KW - Female KW - Immunoglobulin G KW - Immunologic Factors KW - Male KW - Mice, Inbred BALB C KW - N-Acetylmuramoyl-L-alanine Amidase KW - Neutrophils KW - Pneumococcal Infections KW - Pneumococcal Vaccines KW - Pneumonia, Bacterial KW - Sepsis KW - Streptococcus pneumoniae KW - Treatment Outcome TI - Immunization with LytB protein of Streptococcus pneumoniae activates complement-mediated phagocytosis and induces protection against pneumonia and sepsis TY - journal article ER -