TY - JOUR AU - Porta-Pardo, Eduard AU - Kamburov, Atanas AU - Tamborero, David AU - Pons, Tirso AU - Grases, Daniela AU - Valencia, Alfonso AU - Lopez-Bigas, Nuria AU - Getz, Gad AU - Godzik, Adam PY - 2017 DO - 10.1038/nmeth.4364 SN - 1548-7091 UR - http://hdl.handle.net/20.500.12105/17411 AB - Understanding genetic events that lead to cancer initiation and progression remains one of the biggest challenges in cancer biology. Traditionally, most algorithms for cancer-driver identification look for genes that have more mutations than expected... LA - eng KW - NONRANDOM SOMATIC MUTATIONS KW - UTILIZING PROTEIN-STRUCTURE KW - TUMOR TYPES KW - SYSTEMATIC ANALYSIS KW - DRIVING CANCER KW - GENES REGIONS KW - IDENTIFICATION KW - LANDSCAPE KW - DISCOVERY KW - Carcinogenesis KW - Chromosome Mapping KW - Genes, Neoplasm KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Neoplasms TI - Comparison of algorithms for the detection of cancer drivers at subgene resolution TY - journal article ER -